|
KMID : 1101220020340020193
|
|
2002 Volume.34 No. 2 p.193 ~ p.200
|
|
|
The Effect of Microcurrent Therapy on Adjuvant lnduced Rheumatoid Arthritis in Rats
|
|
Lee Byeung-Ok
Hwang Seok-Yeon
Lee Kyung-Moo
Lee Kwang-Joo
Kim Eun-Jung
|
|
|
Abstract
|
|
|
|
Drug therapy for rheumatoid arthritis must be maintained constantly and for the whole life but is apt to induce adverse effects in the gastrointestinal or renal system. Therefore, newer methods are trying to reduce adverse effects. Thirty-two female rats separated into seven groups depending on the therapy or Freund’s adjuvant applied: the Normal control group (n=8) received nothing, Positive control group(n=8) only received adjuvant, MC15 group(n=8) received microcurrent with 15㎂, MC30 group(n=8) received rrucrocurrent with 30㎂. The physical and hematological changes were evaluated in the groups with microcurrent at 15㎂ for 15 rrunutes and 30㎂ for 15 minutes. The summarized results follow. 1. Swelling of forepaw and hindpaw was significantly reduced in MC15 and MC30. 2. Arthritis indices in the MC15 and MC30 group were significantly reduced compared to those in the PCG group. 3.Increases in leukocyte and C-reactive protein concentrations by adjuvant induced rheumatoid arthritis were significantly attenuated by the microcurrent therapy. The change of swelling, arthritis index, gross frature to the naked eye, and hematological findings were siginficantly improved in all groups.
|
|
|
KEYWORD
|
|
|
Complement freund’s adjuvant, Rheumatoid arthritis, Microcurrent therapy, CRP
|
|
|
FullTexts / Linksout information
|
|
|
|
|
|
Listed journal information
|
|
|
|